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January 10, 2014

1/10/2014

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Two papers describing genetic screens using CRISPR/Cas9 in human cells:
http://www.sciencemag.org/content/343/6166/80.full
http://www.sciencemag.org/content/343/6166/84.full
Looks like a little bit of inernal competition at the Broad Institute. The lab with just under 70K sgRNAs lost :-)

It turns out Wnt is not really a morphogen in the classical sense. Or is it?
http://www.nature.com/nature/journal/v505/n7482/full/nature12879.html
Note the precise engineering of the membrane-tethered allele.

A nice evo-devo paper on FoxD3
http://www.sciencedirect.com/science/article/pii/S0012160613006106

Now onto "easy" readings:

Migraine: it's all in your head
http://stm.sciencemag.org/content/6/218/218ra5.full
Could there be a similar placebo effect in your experiments?

Editors of Nature appear to have an obsession with sex lives of the early hominids.
http://www.nature.com/nature/journal/v505/n7481/full/nature12847.html
Is it cyrusification of science?

An interesting trend in scientific publications
http://sciencecareers.sciencemag.org/career_magazine/previous_issues/articles/2014_01_09/caredit.a1400008

And last but not least, is anyone surprised that some ballers are not readers?
http://www.cnn.com/2014/01/09/us/ncaa-athletes-unc-response/index.html?hpt=hp_t3
It just makes the academically strong student athletes (and we do have plenty of these) look bad.

Enjoy!

Darius
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    Disclaimer: This started as a "weekend reading list" meant to encourage students in the lab to think about science and their own future in it. Do not take it seriously: I myself may no longer agree with whatever I wrote here last week.
    - Darius

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