This time we will zoom in on a few worthwhile technical development papers:
In vivo visualization of transcripts in zebrafish
http://dev.biologists.org/content/142/7/1368.full
Has been done in other systems, but cool nonetheless.
Tissue-specific CRISPR/Cas9:
http://www.cell.com/developmental-cell/fulltext/S1534-5807%2815%2900075-1
Same here. The race for fully conditional CRISPR/Cas9 is on…
Smaller Cas9 for packaging into AAV
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature14299.html
All these sequences of semi-random genomes are good for something after all...
And here is an exercise in futility:
http://www.sciencemag.org/content/348/6230/18.full
Why would anyone care?
Now onto “career stuff".
Some pharma jobs are moving out of Philly:
http://www.philly.com/philly/business/20150403_GlaxoSmithKline_moving_Philly_vaccine_R_D_jobs_to_Maryland.html
Fortunately not too far.
As career advice goes, this is pretty good:
http://sciencecareers.sciencemag.org/career_magazine/previous_issues/articles/2015_03_31/caredit.a1500080
I suppose one could call her a grad school dropout. But then again, she clearly had a more rewarding career than many of her fellow students who did not drop out.
I keep bringing up the tough job market for PhDs. Here the postdoc seems to have just realized that:
http://sciencecareers.sciencemag.org/career_magazine/previous_issues/articles/2015_03_30/caredit.a1500078
But while much of the advise is spot on, there is a little too much feel-good baloney for my liking.
Enjoy.
In vivo visualization of transcripts in zebrafish
http://dev.biologists.org/content/142/7/1368.full
Has been done in other systems, but cool nonetheless.
Tissue-specific CRISPR/Cas9:
http://www.cell.com/developmental-cell/fulltext/S1534-5807%2815%2900075-1
Same here. The race for fully conditional CRISPR/Cas9 is on…
Smaller Cas9 for packaging into AAV
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature14299.html
All these sequences of semi-random genomes are good for something after all...
And here is an exercise in futility:
http://www.sciencemag.org/content/348/6230/18.full
Why would anyone care?
Now onto “career stuff".
Some pharma jobs are moving out of Philly:
http://www.philly.com/philly/business/20150403_GlaxoSmithKline_moving_Philly_vaccine_R_D_jobs_to_Maryland.html
Fortunately not too far.
As career advice goes, this is pretty good:
http://sciencecareers.sciencemag.org/career_magazine/previous_issues/articles/2015_03_31/caredit.a1500080
I suppose one could call her a grad school dropout. But then again, she clearly had a more rewarding career than many of her fellow students who did not drop out.
I keep bringing up the tough job market for PhDs. Here the postdoc seems to have just realized that:
http://sciencecareers.sciencemag.org/career_magazine/previous_issues/articles/2015_03_30/caredit.a1500078
But while much of the advise is spot on, there is a little too much feel-good baloney for my liking.
Enjoy.
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